Under the guidance of Dr. A.S. Soin, 20 specialists performed a 16 hour rare Domino liver transplant on two children, a 22-month-old boy Shourya Verma and two-year-old girl Siya Thakur on January 31, 2009, which believed to be the world’s youngest patients to undergo such an operation. Domino liver transplant involves sequential surgery. The team of doctors was divided into three units who prepared the donor liver, Shourya’s own liver and Siya’s diseased liver for removal in three separate operating theaters. Shourya had been cured of Maple Syrup Urine Disease (MSUD) through the transplant that used 20% of his aunt’s liver and his own liver was given to Siya, who was battling liver failure owing to a rare condition called Langerhans’ Cell Histiocytosis (LCH). Shourya is India’s first and the world’s youngest recipient of a living donor liver transplant for MSUD, while Siya is the world’s youngest recipient of a domino liver transplant. Shourya’s aunt Mukta, Shourya, and Siya were operated upon in three different theaters. First, the donor liver and then Shourya’s liver were removed. Shourya got a transplant; then his liver was transplanted into Siya.